Two people were taken to the hospital after a diesel tanker and a Honda Civic collided on Interstate 15, according to Capt. Adam Archuleta with Salt Lake City Fire Department.
One person is in critical condition, the other is in fair condition, Archuleta said.
The semi rolled because of the impact of the crash, spilled fuel and caught fire. The tanker was carrying about 8,000 gallons of fuel.
I-15 is closed from 400 South to 2100 South. The HOV lane is now open.
Authorities used foam and water to put out the fire. They ran out of water at one point.
No other businesses nearby caught fire but the road is damaged. At least 12 to 13 concrete panels (300 feet) will need to be replaced. Crews are planning to work into the evening to install a temporary fix.
A storm drain will also need be assessed after gas leaked inside and caused a smaller explosion.
Archuleta says they don't know how long it will take to clean up the scene. John Gleason with the Utah Department of Transportation (UDOT) says it will take several hours to get the HOV lane open.
Investigators are on scene trying to figure out what exactly happened.
Dash cam video was later released Saturday morning, showing officials responding to the scene and clearing the area.